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Home > Microbiology&virology > HCV Protease > Dasabuvir

Dasabuvir

Catalog No. T3489    CAS 1132935-63-7    Synonyms: ABT-333

Dasabuvir is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intracellular uptake, dasabuvir binds HCV NS5B polymerase and blocks viral RNA synthesis and replication. The HCV NS5B protein is essential for the replication of the HCV RNA genome.

Pack Size Availability Price/USD Quantity
5 mg In stock 58.00
10 mg In stock 104.00
25 mg In stock 229.00
50 mg In stock 365.00
100 mg In stock 683.00
1 mL * 10 mM (in DMSO) In stock 58.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

Dasabuvir is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intracellular uptake, dasabuvir binds HCV NS5B polymerase and blocks viral RNA synthesis and replication. The HCV NS5B protein is essential for the replication of the HCV RNA genome.

Receptor:

NS5B polymerase;

Chemical Information:
Molecular Weight 493.58
Formula C26H27N3O5S
CAS Number 1132935-63-7
Solubility

DMSO: ≥46 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
Reference
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