Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1, hypoxia inducible factor α, and inducible nitric oxide synthase, which contributes to oxidative stress and restored sirtuin 1/AMP-activated protein kinase/peroxisome proliferator-activated receptor-γ coactivator-1α pathway-associated fatty acid oxidation in chronic ethanol-fed mice.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 61.00 | |
5 mg | In stock | $ 141.00 | |
10 mg | In stock | $ 198.00 | |
25 mg | In stock | $ 346.00 | |
50 mg | In stock | $ 513.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 155.00 |
Description | Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1, hypoxia inducible factor α, and inducible nitric oxide synthase, which contributes to oxidative stress and restored sirtuin 1/AMP-activated protein kinase/peroxisome proliferator-activated receptor-γ coactivator-1α pathway-associated fatty acid oxidation in chronic ethanol-fed mice. |
Source |
Molecular Weight | 324.35 |
Formula | C19H18NO4 |
CAS No. | 25459-91-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.24 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
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Demethyleneberberine 25459-91-0 Angiogenesis Chromatin/Epigenetic Immunology/Inflammation Metabolism NF-Κb PI3K/Akt/mTOR signaling P450 NOS NF-κB HIF AMPK Inhibitor Nuclear factor-kappaB inhibit Nuclear factor-κB AMP-activated protein kinase inhibitor