Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 35.00 | |
100 mg | In stock | $ 48.00 | |
200 mg | In stock | $ 61.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 30.00 |
Description | Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically. |
Targets&IC50 | SERT:61 nM (Ki), NET:4 nM (Ki), DAT:78720 nM (Ki) |
Synonyms | NSC-114901, Desmethylimipramine, JB-8181, EX-4355, Norimipramine, G-35020 |
Molecular Weight | 302.842 |
Formula | C18H23ClN2 |
CAS No. | 58-28-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL(181.6 mM)
You can also refer to dose conversion for different animals. More
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Desipramine hydrochloride 58-28-6 GPCR/G Protein Neuroscience Dopamine Receptor Adrenergic Receptor Serotonin Transporter 5-HT Receptor SLC6A3 NSC-114901 5-HTT G 35020 NSC 114901 Dopamine Transporter EX4355 Desipramine NSC114901 Inhibitor JB8181 Desmethylimipramine SERT SLC6A4 inhibit JB-8181 EX-4355 Norimipramine G-35020 JB 8181 EX 4355 DAT Desipramine Hydrochloride G35020 inhibitor