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Desmopressin acetate (16679-58-6 free base)

Catalog No. T5144   CAS 62288-83-9
Synonyms: Desmopressin acetate, DDAVP

Desmopressin acetate (16679-58-6 free base) (DDAVP) is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin acetate (16679-58-6 free base) works by limiting the amount of water that is eliminated in the urine. Desmopressin acetate (16679-58-6 free base) binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates the release of von Willebrand factor from endothelial cells by acting on the V2 receptor.

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Desmopressin acetate (16679-58-6 free base) Chemical Structure
Desmopressin acetate (16679-58-6 free base), CAS 62288-83-9
Pack Size Availability Price/USD Quantity
1 mg In stock $ 45.00
2 mg In stock $ 62.00
5 mg In stock $ 98.00
10 mg In stock $ 148.00
25 mg In stock $ 252.00
50 mg In stock $ 379.00
100 mg In stock $ 567.00
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Purity: 100%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Desmopressin acetate (16679-58-6 free base) (DDAVP) is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin acetate (16679-58-6 free base) works by limiting the amount of water that is eliminated in the urine. Desmopressin acetate (16679-58-6 free base) binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates the release of von Willebrand factor from endothelial cells by acting on the V2 receptor.
Synonyms Desmopressin acetate, DDAVP
Molecular Weight 1129.26
Formula C48H68N14O14S2
CAS No. 62288-83-9

Storage

store at low temperature,keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 50 mg/mL

DMSO: 10 mM

Ethanol: Soluble

TargetMolReferences and Literature

1. Kaufmann JE, et al. Desmopressin (DDAVP) induces NO production in human endothelial cells via V2 receptor- and cAMP-mediated signaling. J Thromb Haemost. 2003 Apr;1(4):821-8. 2. Tsukamoto I. Recent patenting activities in the discovery and development of vasopressin V2 receptor agonists. Expert Opin Ther Pat. 2012 Jun;22(6):579-86.

TargetMolCitations

1. Wang S Q, Li C L, Xu J Q, et al. The Effect of Endolymphatic Hydrops and Mannitol Dehydration Treatment on Guinea Pigs. Frontiers in Cellular Neuroscience. 2022, 16

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Peptide Compound Library Membrane Protein-targeted Compound Library Drug Repurposing Compound Library Anti-Cancer Clinical Compound Library Anti-Cancer Compound Library Bioactive Compounds Library Max Anti-Diabetic Compound Library Orally Active Compound Library

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Keywords

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