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Metabolism GR Dexamethason acetate

Dexamethason acetate

Catalog No. T0947   CAS 1177-87-3
Synonyms: Dexamethasone 21-acetate, Dexamethasone acetate, NSC 39471
Purity 99.22% Datasheet

Dexamethasone Acetate is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones.

Dexamethason acetate, CAS 1177-87-3
Pack Size Availability Price/USD Quantity
5 mg In stock 16.00
10 mg In stock 20.00
25 mg In stock 26.00
50 mg In stock 33.00
100 mg In Stock 40.00
200 mg In Stock 50.00
500 mg In stock 60.00
1 g In stock 86.00
1 mL * 10 mM (in DMSO) In stock 54.00
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Purity 98.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description Dexamethasone Acetate is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones.
Targets&IC50 Annexin A1,   Glucocorticoid Receptor,   IL receptor,   iNOS,  
Animal Research
Animal Model: Sprague-Dawley rats
Synonyms Dexamethasone 21-acetate, Dexamethasone acetate, NSC 39471
Purity 98.00%
Appearance solid
Molecular Weight 434.51
Formula C24H31FO6
CAS No. 1177-87-3

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 81 mg/mL (186.4 mM)

Ethanol: 16 mg/mL (36.8 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Rickard DJ, et al. Dev Biol, 1994, 161(1), 218-228. 1. Rickard DJ, et al. Dev Biol, 1994, 161(1), 218-228. 2. Nagy P, et al. Hepatology, 1998, 28(2), 423-429. 2. Nagy P, et al. Hepatology, 1998, 28(2), 423-429. 3. Kim JB, et al. Brain Res, 2004, 1027(1-2), 1-10. 3. Kim JB, et al. Brain Res, 2004, 1027(1-2), 1-10. 4. Wu CY, et al. J Immunol. 1998, 161(6), 2723-2730. 4. Wu CY, et al. J Immunol. 1998, 161(6), 2723-2730. 5. Blanco FJ, et al. J Rheumatol, 1999, 26(6), 1366-1373. 5. Blanco FJ, et al. J Rheumatol, 1999, 26(6), 1366-1373. 6. Yamamoto K, et al. FEBS Lett, 2000, 465(2-3), 103-106.

Related Compound Libraries

This product is contained In the following compound libraries:
Approved Drug Library Bioactive Compound Library Inhibitor Library Anti-cancer Compound Library Anti-infection Compound Library Autophagy Compound Library Endocrinology-Hormones Library FDA-approved Drug Library Immunology/Inflammation Compound Library Antibiotics Library Cytokine Inhibitor Library GPCR Compound Library Fluorochemical Library Anti-Metabolism Disease Compound Library

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