Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory-proprostaglandins.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 42.00 | |
5 g | Inquiry | $ 51.00 | |
10 g | Inquiry | $ 83.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 46.00 |
Description | Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory-proprostaglandins. |
Targets&IC50 | COX-1 (human, CHO cells):4 nM, COX-1 (ovine):5.1 μM, COX-1 (ovine):0.84 μM, COX-2 (human, CHO cells):1.3 nM |
Synonyms | Diclofenacum, Voltaren |
Molecular Weight | 296.15 |
Formula | C14H11Cl2NO2 |
CAS No. | 15307-86-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 199.2 mM
You can also refer to dose conversion for different animals. More
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Diclofenac 15307-86-5 Apoptosis Immunology/Inflammation Neuroscience COX NSCs stem COX-1 neural CHO cascade anti-inflammatory cells ovine COX-2 Diclofenacum Inhibitor Cyclooxygenase caspase inhibit Voltaren inhibitor