Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol is a competitive inhibitor of vitamin K epoxidereductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.
Pack Size | Availability | Price/USD | Quantity |
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500 mg | In stock | $ 41.00 |
Description | Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol is a competitive inhibitor of vitamin K epoxidereductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting. |
Targets&IC50 | PDK1:19.42 μM, NQO1:0.37 μM |
Source |
Synonyms | Dicumarol |
Molecular Weight | 336.3 |
Formula | C19H12O6 |
CAS No. | 66-76-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6.73mg/mL (20 mM)
Ethanol: 62 mg/mL (184.4 mM)
H2O: Insoluble
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Dicoumarol 66-76-2 Metabolism PI3K/Akt/mTOR signaling Dehydrogenase PDK NADPH PDH kinase Dicumarol inhibit PDHK Pyruvate dehydrogenase kinase Inhibitor inhibitor