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Dihydroberberine

Catalog No. T8189 CAS 483-15-8

Synonyms: inhibit, KcsA, Potassium Channel, Dihydroberberine, Inhibitor, HSP, Heat shock proteins

Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interaction with hERG.

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Dihydroberberine, CAS 483-15-8

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	inhibit, KcsA, Potassium Channel, Dihydroberberine, Inhibitor, HSP, Heat shock proteins
Molecular Weight	337.375
Formula	C20H19NO4
CAS No.	483-15-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Yu D, et al. Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells. PLoS One. 2017 Aug 1;12(8):e0181823.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Anti-Lung Cancer Compound Library Traditional Chinese Medicine Monomer Library Tibetan medicine Compound Library Anti-Pancreatic Cancer Compound Library Natural Product Library for HTS Anti-Tumor Natural Product Library Immunology/Inflammation Compound Library Anti-Metabolism Disease Compound Library Alkaloid Natural Product Library

Related Products

Related compounds with same targets

VU 0240551 Dihydroberberine Endoxifen Z-isomer hydrochloride NS309 AZD-5672 BMS-599626 ARRY-380 (analog ) Sigma-1 receptor antagonist 3

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.