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Dimethyl lithospermate B

Catalog No. T8299 CAS 875313-64-7

Synonyms: dmLSB

Purity 99.62% Datasheet

Dimethyl lithospermate B is a selective Na+ channel agonist.

Dimethyl lithospermate B, CAS 875313-64-7

Pack Size	Availability	Price/USD	Quantity
1 mg	In stock	240.00
5 mg	In stock	713.00

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Purity 98.00%

Datasheet

Purity 99.62%

HNMR HPLC Datasheet

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Dimethyl lithospermate B is a selective Na+ channel agonist.
Targets&IC50	Sodium Channel,
In vitro	Dimethyl lithospermate B slows inactivation of sodium current (INa), leading to the increased inward current during the early phases of the action potential [1][2].

Synonyms	dmLSB
Purity	98.00%
Appearance	solid
Molecular Weight	746.7
Formula	C38H34O16
CAS No.	875313-64-7

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Fish JM, et al. Dimethyl lithospermate B, an extract of Danshen, suppresses arrhythmogenesis associated with the Brugada syndrome. Circulation. 2006 Mar 21;113(11):1393-400. 2. Yoon JY, et al. A novel Na+ channel agonist, dimethyl lithospermate B, slows Na+ current inactivation and increases action potential duration in isolated rat ventricular myocytes. Br J Pharmacol. 2004 Nov;143(6):765-73.

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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