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Doramectin

Catalog No. T0969 CAS 117704-25-3

Synonyms: Dectomax, Cyclohexylavermectin B1

Doramectin (Dectomax) is an antiparasitic agent.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Doramectin, CAS 117704-25-3

Pack Size	Availability	Price/USD
50 mg	In stock	$ 38.00
100 mg	In stock	$ 53.00
500 mg	In stock	$ 91.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 98.4%

Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Doramectin (Dectomax) is an antiparasitic agent.

Kinase Assay

To determine which caspases are involved in apoptosis induced by taxol, caspase-3 inhibitor (DEVD-CHO), caspase-6 inhibitor (Z-VEID-FMK), caspase-8 inhibitor (Z-IETD-FMK or IETD-CHO), caspase-9 inhibitors (Z-LEHD-FMK or LEHD-CHO), and caspase-10 inhibitor (Z-AEVD-FMK) are used. These caspase inhibitors are dissolved in dimethyl sulfoxide (Me2SO); the final concentration of Me2SO is 0.1%. Cells (5×105) are preincubated in the presence or absence of 100 μM?each of these inhibitors for 3 h at 37°C then treated with or without 0.1, 0.5, and 1 μM?Paclitaxel for 48 h and processed for annexin V binding assay.

Synonyms	Dectomax, Cyclohexylavermectin B1
Molecular Weight	899.11
Formula	C50H74O14
CAS No.	117704-25-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 30 mg/mL (33.37 mM)

References and Literature

1. Davey RB, et al. Exp Appl Acarol. 2012 Apr;56(4):365-74.

Related compound libraries

This product is contained In the following compound libraries：

Antiparasitic Natural Product Library Microbial Natural Product Library Anti-Parasitic Compound Library Bioactive Compounds Library Max Natural Product Library Human Metabolite Library Anti-Infection Compound Library FDA-Approved & Pharmacopeia Drug Library Immunology/Inflammation Compound Library Bioactive Compound Library

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Related compounds with same targets

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Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Doramectin 117704-25-3 Microbiology/Virology Others Antibiotic Parasite Dectomax Inhibitor inhibit Cyclohexylavermectin B1 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.