Powder: -20°C for 3 years | In solvent: -80°C for 1 year
The Ki value of DOT1L-in-1 is 2pm.It is a highly effective, selective and novel Dot1L inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 2,720.00 | |
50 mg | 10-14 weeks | $ 3,580.00 | |
100 mg | 10-14 weeks | $ 4,900.00 |
Description | The Ki value of DOT1L-in-1 is 2pm.It is a highly effective, selective and novel Dot1L inhibitor. |
Targets&IC50 | Dot1L(ki):ki:2 pM |
In vitro | Dot1l-in-1 significantly inhibited H3K79 dimethylation (IC50 = 3 nM) and HoxA9 promoter (IC50 = 17 nM) IN HeLa and MOLM-13 cells.Dot1l-in-1 effectively inhibited the proliferation of mL-recombinant human leukemia cell line MV4-11 carrying carcinogenic MLL-AF4 fusion (IC50 = 5 nM). |
Molecular Weight | 646.21 |
Formula | C32H36ClN9O2S |
CAS No. | 2088518-50-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Dot1L-IN-1 2088518-50-5 Chromatin/Epigenetic Histone Methyltransferase Dot1LIN1 Dot-1L-IN-1 Dot1L IN 1 inhibitor inhibit