Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EED226-COOH, derived from EED226, serves as a ligand targeting the EED protein for PROTAC applications. It attaches to a VHL ligand through a linker, culminating in the formation of UNC6852, which specifically degrades PRC2[1].
Description | EED226-COOH, derived from EED226, serves as a ligand targeting the EED protein for PROTAC applications. It attaches to a VHL ligand through a linker, culminating in the formation of UNC6852, which specifically degrades PRC2[1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Molecular Weight | 335.32 |
Formula | C17H13N5O3 |
CAS No. | T17931 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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EED226-COOH T17931 Others EED-226-COOH EED226COOH EED226 COOH inhibitor inhibit