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ENMD-1068 HCl

Catalog No. T27267 CAS 789488-77-3

Synonyms: ENMD-1068 HCl, ENMD 1068, ENMD-1068, ENMD1068, ENMD-1068 hydrochloride

ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.

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ENMD-1068 HCl, CAS 789488-77-3

Pack Size	Availability	Price/USD
10 mg	In stock	$ 50.00
25 mg	In stock	$ 87.00
50 mg	In stock	$ 137.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.

Synonyms	ENMD-1068 HCl, ENMD 1068, ENMD-1068, ENMD1068, ENMD-1068 hydrochloride
Molecular Weight	283.41
Formula	C15H29N3O2
CAS No.	789488-77-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (194.07 mM)

References and Literature

1. Ibrahim Sulaiman, et al. Molecularly targeted therapies for asthma: Current development, challenges and potential clinical translation. Pulm Pharmacol Ther. 2016 Oct;40:52-68. 2. Hyosun Jang, et al. Skin pH Is the Master Switch of Kallikrein 5-Mediated Skin Barrier Destruction in a Murine Atopic Dermatitis Model. J Invest Dermatol. 2016 Jan;136(1):127-35. 3. Ahmed Nadeem, et al. Proteinase activated receptor-2-mediated dual oxidase-2 up-regulation is involved in enhanced airway reactivity and inflammation in a mouse model of allergic asthma. Immunology. 2015 Jul;145(3):391-403. 4. Nadeem A, Alharbi NO, Vliagoftis H, Tyagi M, Ahmad SF, Sayed-Ahmed MM. Proteinase activated receptor-2-mediated dual oxidase-2 up-regulation is involved in enhanced airway reactivity and inflammation in a mouse model of allergic asthma. Immunology. 2015 Jul;145(3):391-403. doi: 10.1111/imm.12453. PubMed PMID: 25684443; PubMed Central PMCID: PMC4479538.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Inhibitor Library Bioactive Compounds Library Max Bioactive Compound Library

Related Products

Related compounds with same targets

Protease-Activated Receptor-1, PAR-1 Agonist acetate TFLLR-NH2 Vorapaxar TRAP-6 amide acetate Thrombin Receptor Activator for Peptide 5 (TRAP-5) Protease-Activated Receptor-2, amide tcY-NH2 TFA(327177-34-4 free base) PAR-2-IN-1

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

ENMD-1068 HCl 789488-77-3 GPCR/G Protein Protease-activated Receptor ENMD1068 Hydrochloride ENMD1068 HCl ENMD 1068 HCl ENMD 1068 Hydrochloride ENMD-1068 Hydrochloride ENMD 1068 ENMD-1068 ENMD1068 ENMD-1068 hydrochloride inhibitor inhibit

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