Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 96.00 | |
5 mg | In stock | $ 217.00 | |
10 mg | In stock | $ 316.00 | |
25 mg | In stock | $ 532.00 | |
50 mg | In stock | $ 769.00 |
Description | EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells. |
Targets&IC50 | Epac:4 µM |
In vitro | EPAC 5376753 decreases the conformational changes of EPAC necessary for its activation. EPAC 5376753 inhibits EPAC signaling in cells and EPAC-mediated migration in fibroblasts[1]. |
Synonyms | 5-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione |
Molecular Weight | 367.21 |
Formula | C15H8Cl2N2O3S |
CAS No. | 302826-61-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.68 mg/mL (10.01 mM)
You can also refer to dose conversion for different animals. More
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EPAC 5376753 302826-61-5 GPCR/G Protein cAMP 5-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione EPAC5376753 EPAC-5376753 inhibitor inhibit