Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 437.00 | |
10 mg | In stock | $ 646.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,380.00 | |
100 mg | In stock | $ 1,860.00 | |
500 mg | In stock | $ 3,720.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 469.00 |
Description | Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. |
In vitro | Elubrixin inhibits neutrophil CD11b upregulation with an IC50 of 260.7 nM and shapes change with an IC50 of 310.5 nM. Elubrixin has an inhibitory effect on neutrophils in a dose-dependent manner[3]. |
Synonyms | SB-656933 |
Molecular Weight | 463.31 |
Formula | C17H17Cl2FN4O4S |
CAS No. | 688763-64-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (21.58 mM)
You can also refer to dose conversion for different animals. More
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Elubrixin 688763-64-6 Autophagy GPCR/G Protein Immunology/Inflammation IL Receptor CXCR airway Inhibitor inhibit Interleukin Related SB-656933 IL-8 CXC chemokine receptors neutrophil-mediated CXCR2 anti-inflammatory SB656933 CD11b bowel SB 656933 inhibitor