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Endoxifen (Z-isomer)

Catalog No. T2280 CAS 112093-28-4

Synonyms: Potassium Channel, Endoxifen (Z-isomer), Endoxifen (Zisomer), Endoxifen (Z isomer), Inhibitor, KcsA, inhibit, Endoxifen Z-isomer, Estrogen Receptor/ERR

Endoxifen (EDX) is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptors that also inhibits aromatase activity.

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Endoxifen (Z-isomer), CAS 112093-28-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Endoxifen (EDX) is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptors that also inhibits aromatase activity.
Targets&IC50	hERG:1.6 μM

Synonyms	Potassium Channel, Endoxifen (Z-isomer), Endoxifen (Zisomer), Endoxifen (Z isomer), Inhibitor, KcsA, inhibit, Endoxifen Z-isomer, Estrogen Receptor/ERR
Molecular Weight	373.496
Formula	C25H27NO2
CAS No.	112093-28-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Chae YJ, et al. Eur J Pharmacol. 2015 Apr 5;752:1-7.2. Wu X, et al. Breast Y Res. 2011 Mar 10;13(2):R27.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Anti-Lung Cancer Compound Library GPCR Compound Library Cytokine Inhibitor Library Endocrinology-Hormone Compound Library Anti-Pancreatic Cancer Compound Library Inhibitor Library Ion Channel Inhibitor Library Immunology/Inflammation Compound Library Drug Repurposing Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

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