Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Estradiol benzoate (Benzhormovarine) is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 45.00 | |
1 g | In stock | $ 53.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Estradiol benzoate (Benzhormovarine) is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. |
Targets&IC50 | ERα (mouse):2.3 nM, ERα (human):28 nM |
In vitro | Estradiol benzoate is asynthetic ester, specifically the 3-benzoyl ester, of the natural estrogen, estradiol. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol. [1] |
Synonyms | Benzoestrofol, Benzhormovarine, Benovocylin |
Molecular Weight | 376.49 |
Formula | C25H28O3 |
CAS No. | 50-50-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 70 mg/mL (185.9 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Estradiol benzoate 50-50-0 Endocrinology/Hormones Estrogen/progestogen Receptor Estrogen Receptor/ERR Benzoestrofol Benzhormovarine inhibit Estradiol Benzoate Inhibitor Benovocylin Estradiol inhibitor