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Ethyl cinnamate

Catalog No. TN1624 CAS 103-36-6

Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl cinnamate can inhibit the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-dependent manner, with respective IC50 values of 0.30 mM and 0.38 mM.

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Ethyl cinnamate, CAS 103-36-6

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1 g	In stock	$ 30.00
1 mL * 10 mM (in DMSO)	In stock	$ 29.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl cinnamate can inhibit the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-dependent manner, with respective IC50 values of 0.30 mM and 0.38 mM.
Targets&IC50	Tonic contractions (chenylephrine-induced):0.38 mM, Tonic contractions (high K+-induced):0.30 mM
In vitro	Parameters, including biomass, F(v)/F(m) (maximal photochemical efficiency of PSII), Ф(PSII) (actual photochemical efficiency of PSII in the light), FDA, and PI staining fluorescence, were measured. The results showed the following: (1) The inhibition on biomass increased as the exposure concentration increased. 1 mg/L Ethyl cinnamate was sufficient to reduce the total biomass of C. vulgaris. The 48-h and 72-h EC50 values were 2.07 mg/L (1.94-2.20) and 1.89 mg/L (1.82-1.97). (2) After 24 h of exposure to 2-4 mg/L Ethyl cinnamate, the photosynthesis of C. vulgaris almost ceased, manifesting in DФ(PSII) being close to zero. After 72 h of exposure to 4 mg/L Ethyl cinnamate, the Fv /Fm of C. vulgaris dropped to zero. (3) Ethyl cinnamate also affected the cellular physiology of C. vulgaris, but these effects resulted in the inhibition of cell yield rather than cell death[1]
Source	Natural Products > Lauraceae > Cinnamomum

Molecular Weight	176.21
Formula	C11H12O2
CAS No.	103-36-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (283.75 mM), Sonification is recommended

References and Literature

1. Jiao Y, et al. Toxic Effects of Ethyl Cinnamate on the Photosynthesis and Physiological Characteristics of Chlorella vulgaris Based on Chlorophyll Fluorescence and Flow Cytometry Analysis. ScientificWorldJournal. 2015;2015:107823. 2. Anika Klingberg, et al. Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy. J Am Soc Nephrol. 2017 Feb;28(2):452-459. 3. S P Bhatia, et al. Fragrance material review on ethyl cinnamate. Food Chem Toxicol. 2007;45 Suppl 1:S90-4.

Related compound libraries

This product is contained In the following compound libraries：

Miao medicine Compound Library Membrane Protein-targeted Compound Library Tobacco Monomer Library Neuronal Signaling Compound Library Food Additive Library Selected Plant-Sourced Compound Library Pyroptosis Compound Library Anti-Cardiovascular Disease Compound Library Mitochondria-Targeted Compound Library Cuproptosis Compound Library

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Keywords

Ethyl cinnamate 103-36-6 Immunology/Inflammation Membrane transporter/Ion channel Metabolism Calcium Channel NO Synthase ROS Inhibitor fragrance inhibit clearing reagent inhibitor

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