Powder: -20°C for 3 years | In solvent: -80°C for 1 year
F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 95.00 | |
2 mg | In stock | $ 137.00 | |
5 mg | In stock | $ 239.00 | |
10 mg | In stock | $ 383.00 | |
25 mg | In stock | $ 647.00 | |
50 mg | In stock | $ 922.00 | |
100 mg | In stock | $ 1,250.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 297.00 |
Description | F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM). |
Targets&IC50 | 5-HT1A:3.4 nM(ki) |
In vivo | F-15599 exerted very potent (ID50 = 0.095 and 0.0059 mg/kg, respectively) anti-aggressive effects in male WTG rats. At 4.5-fold higher dose ranges, the anti-aggressive effects were accompanied by concomitant motor inactivity and/or reduction of social engagement. Pretreatment with WAY-100635 counteracted the behavioural effects of both agonists[1]. |
Animal Research | F-15599 agonists were acutely administered intraperitoneally in aggressive resident male WTG rats confronting an intruder[1]. |
Molecular Weight | 394.85 |
Formula | C19H21ClF2N4O |
CAS No. | 635323-95-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (56.98 mM)
You can also refer to dose conversion for different animals. More
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F-15599 635323-95-4 GPCR/G Protein Neuroscience 5-HT Receptor NLX-101 inhibit F15599 Serotonin Receptor NLX 101 NLX101 F 15599 5-hydroxytryptamine Receptor Inhibitor inhibitor