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FASN-IN-3

Catalog No. T11557 CAS 2097262-60-5

FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).

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FASN-IN-3, CAS 2097262-60-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 116.00
5 mg	In stock	$ 289.00
10 mg	In stock	$ 478.00
25 mg	In stock	$ 789.00
50 mg	In stock	$ 1,080.00
100 mg	In stock	$ 1,480.00
1 mL * 10 mM (in DMSO)	In stock	$ 318.00

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Purity: 98.22%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).

In vitro

For monocytes, FASN-IN-3 treatment reduces the level of IL-1 beta resulting from LTA stimulation whereas there is only a slight reduction after LPS stimulation.Human PBMC and monocytes in cell cultures are stimulated with lipopolysaccharide (LPS), a Toll 4 receptor agonist, or lipoteichoic acid (LTA), a Toll 2 receptor agonist. Stimulation with either LPS or LTA plus DMSO, the solvent for FASN-IN-3 , results in secretion of IL-1 beta. FASN inhibitor 1 treatment of PBMC, which is a mixed population of mononuclear cells including both lymphocytes and monocytes, reduces the level of IL-1 beta resulting from either LPS or LTA stimulation.

Molecular Weight	384.47
Formula	C24H24N4O
CAS No.	2097262-60-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 33.33 mg/mL (86.69 mM), Sonification and heating to 80℃ are recommended.

References and Literature

1. Buckley, Douglas I, et al. HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS. US20170119786A1

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Obesity Compound Library NO PAINS Compound Library Lipid Metabolism Compound Library Bioactive Compound Library Metabolism Compound Library Anti-Cancer Metabolism Compound Library Bioactive Compounds Library Max Anti-Metabolism Disease Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

FASN-IN-3 2097262-60-5 Metabolism Fatty Acid Synthase Fatty Acid Synthase (FASN) Inhibitor inhibit FASNIN3 FASN IN 3 inhibitor

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