Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FCE 28654 is a water-soluble acyl-CoA inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | FCE 28654 is a water-soluble acyl-CoA inhibitor. |
Targets&IC50 | ACAT (rabbit aorta):2.55 μM , ACAT (rabbit intestine):1.08 μM , ACAT (monkey liver):5.69 μM |
In vitro | FCE 28654 is a ACAT inhibitor, weakly inhibiting ACAT in microsomes from rabbit aorta and intestine, and monkey liver(IC50s of 2.55, 1.08 and 5.69 μM, respcetively). |
In vivo | In hypercholesterolemic rats, FCE 28654 (15 mg/kg, p.o.) dramatically decreases blood cholesterol and modifies the hepatic cholesterol pattern via enhancing the free/esterified cholesterol ratio. FCE 28654 (100 mg/kg, p.o.) reduces microsomal ACAT activity rat plasma. |
Molecular Weight | 506.53 |
Formula | C25H35N2O7P |
CAS No. | 169474-77-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
FCE 28654 169474-77-5 FCE28654 FCE-28654 inhibitor inhibit