keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fast Green FCF (FD&C Green No. 3), a safe biocompatible color additive, has been suggested to mitigate chronic pain.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 41.00 | |
1 g | In stock | $ 48.00 |
Description | Fast Green FCF (FD&C Green No. 3), a safe biocompatible color additive, has been suggested to mitigate chronic pain. |
In vivo | Pretreatment of Fast green FCF (100 mg/kg, i.p. daily for 7 days) alleviated depressive-like behavior in LPS-treated mice.?Fast green FCF suppressed the LPS-induced microglial and astrocyte activation in the hippocampus.?Fast green FCF decreased the mRNA and protein levels of Toll-like receptor 4 (TLR4) and Myeloid differentiation primary response 88 (Myd88) and suppressed the phosphorylation of nuclear factor-κB (NF-κB) in the hippocampus of LPS-treated mice.?Fast green FCF also downregulated hippocampal tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6, but did not alter the level of the brain-derived neurotrophic factor (BDNF) in the hippocampus of LPS-treated mice.?The molecular docking simulation predicts that Fast green FCF may interact with TLR4 and interrupt the formation of the TLR4-MD2 complex[1]. |
Synonyms | C.I. 42053, Food green 3, FD&C Green No. 3 |
Molecular Weight | 808.85 |
Formula | C37H34N2Na2O10S3 |
CAS No. | 2353-45-9 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 10 mg/mL (12.36 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Fast Green FCF 2353-45-9 Others C.I. 42053 Food green-3 Food green 3 Inhibitor Food green3 inhibit FD&C Green No. 3 inhibitor