store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fosmidomycin sodium salt (FR-31564 sodium salt) is an anti-infective antibiotic with anti-malarial activity that inhibits both Gram-negative and Gram-positive bacteria.
Description | Fosmidomycin sodium salt (FR-31564 sodium salt) is an anti-infective antibiotic with anti-malarial activity that inhibits both Gram-negative and Gram-positive bacteria. |
In vitro | FR-31564 is a novel phosphonic acid antibiotic that exhibits activity against most Gram-negative and Gram-positive bacteria, except for mucoid Pseudomonas aeruginosa and glucose non-fermenting Gram-negative rods (excluding Pseudomonas aeruginosa).[1][2][3]. |
In vivo | After oral administration of 50 or 100 mg/kg of Fosmidomycin sodium salt, animals showed no parasites in their bodies, while treatment with 20 mg/kg resulted in a parasitemia rate of less than 1%. However, recurrence was observed when treatment was discontinued after 4 days. Complete cure was achieved in mice treated with 30 mg/kg of Fosmidomycin sodium salt 8 days.Animals apparently free of parasites are observed after intraperitoneal treatment[2]. |
Synonyms | FR-31564 sodium salt |
Molecular Weight | 205.08 |
Formula | C4H9NNaO5P |
CAS No. | 66508-37-0 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 20 mg/mL (97.52 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Fosmidomycin sodium salt 66508-37-0 Microbiology/Virology Antibiotic Parasite Fosmidomycin sodium FR31564 FR-31564 sodium salt FR-31564 FR 31564 inhibitor inhibit