store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-κB, resulting in the suppression of secretion of uPA.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 283.00 | |
5 mg | In stock | $ 853.00 | |
10 mg | Inquiry | $ 1,150.00 | |
50 mg | Inquiry | Inquiry |
Description | Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-κB, resulting in the suppression of secretion of uPA. |
In vitro | In highly invasive human breast cancer cells, Ganoderic acid H suppressed growth (cell proliferation and colony formation) and invasive behavior (adhesion, migration and invasion) of MDA-MB-231 cells[1]. Furthermore, the activity of Ganoderic acid H is linked to the hydroxylation in the positions 7 and 3 in its triterpene lanostane structure[1]. Ganoderic acid H could be a promising natural agent for the therapy of invasive breast cancers[1]. |
Source |
Molecular Weight | 572.69 |
Formula | C32H44O9 |
CAS No. | 98665-19-1 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (139.69 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Ganoderic acid H 98665-19-1 Cell Cycle/Checkpoint DNA Damage/DNA Repair NF-Κb NF-κB CDK DNA/RNA Synthesis inhibit Inhibitor inhibitor