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Geranylgeraniol

Catalog No. TN6714   CAS 24034-73-9
Synonyms: FT-0626663, Tetraprenol, CJ24095, CJ 24095, FT0626663, CJ-24095

Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) protects monocytes against statin-induced cytotoxicity and suppresses the growth of Mycobacterium.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Geranylgeraniol Chemical Structure
Geranylgeraniol, CAS 24034-73-9
Pack Size Availability Price/USD Quantity
50 mg In stock $ 30.00
100 mg In stock $ 39.00
200 mg In stock $ 55.00
1 mL * 10 mM (in DMSO) In stock $ 39.00
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Purity: 99.89%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) protects monocytes against statin-induced cytotoxicity and suppresses the growth of Mycobacterium.
Synonyms FT-0626663, Tetraprenol, CJ24095, CJ 24095, FT0626663, CJ-24095
Molecular Weight 290.48
Formula C20H34O
CAS No. 24034-73-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: >25 mg/ml

TargetMolReferences and Literature

1. Schumacher MM, et al. The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase. Elife. 2015 Mar 5;4. 2. Fernandes NV, et al. Geranylgeraniol suppresses the viability of human DU145 prostate carcinoma cells and the level of HMG CoA reductase. Exp Biol Med (Maywood). 2013 Nov 1;238(11):1265-74. 3. Zafar S, et al. Zoledronic acid and geranylgeraniol regulate cellular behaviour and angiogenic gene expression in human gingival fibroblasts. J Oral Pathol Med. 2014 Oct;43(9):711-21. 4. Pabst AM, et al. Isoprenoid geranylgeraniol: the influence on cell characteristics of endothelial progenitor cells after bisphosphonate therapy in vitro. Clin Oral Investig. 2015 Sep;19(7):1625-33.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Anti-Tumor Natural Product Library Natural Product Library Anti-Cancer Compound Library Traditional Chinese Medicine Monomer Library Selected Plant-Sourced Compound Library Bioactive Compounds Library Max Food as Medicine Compound Library Bioactive Compound Library Natural Product Library for HTS

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Keywords

Geranylgeraniol 24034-73-9 Apoptosis mitochondria neuronal death neuroinflammation apoptosis FT-0626663 Tetraprenol cholesterol pathway NF-κB inhibit CJ24095 LPS-induced CJ 24095 microglial inflammation Nuclear factor-kappaB Nuclear factor-κB FT0626663 FT 0626663 mevalonate CJ-24095 Inhibitor inhibitor

 

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