Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 179.00 | |
5 mg | In stock | $ 449.00 | |
10 mg | In stock | $ 659.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,390.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 497.00 |
Description | Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR). |
In vitro | In the liver, obeticholic acid undergoes conjugation with glycine to produce glyco-obeticholic acid, subsequently secreted into bile. Upon reaching the ileum and colon, microorganisms deconjugate this compound back into its original form, obeticholic acid, facilitating its reabsorption or fecal excretion. |
Molecular Weight | 477.68 |
Formula | C28H47NO5 |
CAS No. | 863239-60-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (104.67 mM)
You can also refer to dose conversion for different animals. More
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Glyco-Obeticholic acid 863239-60-5 Metabolism FXR NR1H4 Inhibitor ileum colon microorganisms GlycoObeticholic acid Glyco Obeticholic acid metabolite,liver inhibit inhibitor