Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Golgicide A is a potent and rapidly reversible GBF1 inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 57.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 208.00 | |
50 mg | In stock | $ 397.00 | |
100 mg | In stock | $ 597.00 | |
500 mg | In stock | $ 1,320.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 62.00 |
Description | Golgicide A is a potent and rapidly reversible GBF1 inhibitor. |
In vitro | Golgicide A inhibits the effect of shiga toxin on protein synthesis with an IC50 of 3.3 μM. Golgicide A causes a decrease in GBF1-mediated Arf1 activation, arrests secretion of soluble and membrane-anchored proteins and then impairs retrograde toxin transport. [1] Golgicide A decreases HCV RNA levels in FLRP1 cells and J6/JFH1 cells. In addition, Golgicide A causes redistribution of NS5A and accumulation of infectious viral particles in J6/JFH1 cells. [2] |
Molecular Weight | 284.3 |
Formula | C17H14F2N2 |
CAS No. | 1139889-93-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 14.2 mg/mL (50 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Golgicide A 1139889-93-2 Microbiology/Virology Others Virus Protease Enterovirus Rhinovirus HEVs HRVs HEV GCA inhibit Inhibitor HRV inhibitor