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Grp94 Inhibitor-1

Catalog No. T7261   CAS 2234897-35-7

Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).

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Grp94 Inhibitor-1 Chemical Structure
Grp94 Inhibitor-1, CAS 2234897-35-7
Pack Size Availability Price/USD Quantity
5 mg In stock $ 41.00
10 mg In stock $ 66.00
25 mg In stock $ 122.00
50 mg In stock $ 197.00
100 mg In stock $ 341.00
1 mL * 10 mM (in DMSO) In stock $ 46.00
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Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).
Targets&IC50 Grp94:2 nM
Molecular Weight 352.47
Formula C22H28N2O2
CAS No. 2234897-35-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (70.93 mM)

TargetMolReferences and Literature

1. Jiang F , Guo A P , Xu J C , et al. Discovery of a Potent Grp94 Selective Inhibitor with Anti-inflammatory Efficacy in a Mouse Model of Ulcerative Colitis[J]. Journal of Medicinal Chemistry, 2018.

TargetMolCitations

1. Hao M, Guo Y, Zhang Z, et al. 6-acrylic phenethyl ester-2-pyranone derivative induces apoptosis and G2/ M arrest by targeting GRP94 in colorectal cancer. Bioorganic Chemistry. 2022, 123: 105802 2. Lu Y, Li D, Ai H, et al.Glucose-regulated protein 94 facilitates the proliferation of the Bombyx mori nucleopolyhedrovirus via inhibiting apoptosis.International Journal of Biological Macromolecules.2023: 127158.

Related compound libraries

This product is contained In the following compound libraries:
Cytoskeletal Signaling Pathway Compound Library Inhibitor Library Anti-Breast Cancer Compound Library Endocrinology-Hormone Compound Library Bioactive Compounds Library Max Bioactive Compound Library Metabolism Compound Library Exosome Compound Library Endoplasmic Reticulum Stress Compound Library GPCR Compound Library

Related Products

Related compounds with same targets
Ginsenoside Rb2 Benzyl nicotinate Vincamine P2Y2R/GPR17 antagonist 1 D-Kynurenine Lodoxamide GW9508 TUG-1375

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Grp94 Inhibitor-1 2234897-35-7 Cytoskeletal Signaling Endocrinology/Hormones GPCR/G Protein Metabolism HSP GPR Heat shock proteins integrin αL Inhibitor inhibit integrin α2 Grp-94 Inhibitor-1 Grp94 Inhibitor 1 Grp94 Inhibitor1 Grp94 inhibitor

 

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