Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1.2 nM, and <500 nM for HDAC1, HDAC6, mTOR and PI3Kα).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 6-8 weeks | $ 446.00 | |
25 mg | 6-8 weeks | $ 1,430.00 | |
50 mg | 6-8 weeks | $ 1,860.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα). |
Targets&IC50 | mTOR:1.2 nM, HDAC6:1.8 nM, HDAC1:0.19 nM |
In vitro | HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in the G0/G1 phase and induces tumor cell apoptosis with low toxicity in vivo. |
Molecular Weight | 566.65 |
Formula | C28H38N8O5 |
CAS No. | 2271413-06-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 32.5 mg/mL (57.35 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
HDACs/mTOR Inhibitor 1 2271413-06-8 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC inhibitor inhibit