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Cytoskeletal Signaling HSP HM03

HM03

Catalog No. T8668   CAS 500565-15-1
Purity 98.00% Datasheet

HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.

HM03, CAS 500565-15-1
Pack Size Availability Price/USD Quantity
5 mg Inquiry 57.00
10 mg Inquiry 100.00
25 mg Inquiry 199.00
50 mg Inquiry 358.00
100 mg Inquiry 617.00
200 mg Inquiry 919.00
1 mL * 10 mM (in DMSO) Inquiry 69.00
Bulk Size: Please Quote for Discount
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Purity 98.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.
Targets&IC50 HSPA5,  
Synonyms
Purity 98.00%
Appearance solid
Molecular Weight 462.97
Formula C26H27ClN4O2
CAS No. 500565-15-1

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 125 mg/mL (270.00 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Huang M , Li Z , Li D , et al. Structure-based design of HSPA5 inhibitors: From peptide to small molecule inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2013, 23(10):3044-3050.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.