Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by increasing ROS levels, and damaging cell walls.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 64.00 | |
5 mg | In stock | $ 155.00 | |
10 mg | In stock | $ 263.00 | |
25 mg | In stock | $ 447.00 | |
50 mg | In stock | $ 646.00 | |
100 mg | In stock | $ 888.00 |
Description | HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by increasing ROS levels, and damaging cell walls. |
In vitro | Photodynamic therapy with hypocrellin B remarkably induced apoptosis and inhibited adhesion and migration of cancer cells in vitro. |
Cell Research | Human ovarian cancer HO-8910 cell as a cancer model cell was incubated with hypocrellin B at a concentration of 2.5 μM for 5 h and irradiated by light from a light-emitting diodes (LED) source. Cell apoptosis was analyzed by flow cytometry with annexin V/propidium iodide (PI) staining and nuclear staining 6 h after hypocrellin B photoirradiation. Cell adhesion was assessed using the 3-(4, 5-dimthylthiazol-2-yl)-2, 5 diphenyl-tetrazolium bromide (MTT) assay 4 h after photodynamic treatment. Cell migration was measured 48 h after photodynamic treatment. |
Molecular Weight | 528.51 |
Formula | C30H24O9 |
CAS No. | 123940-54-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
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HYPOCRELLIN B 123940-54-5 Apoptosis Microbiology/Virology Antifungal Parasite Antimicrobial Pseudomonas aeruginosa Hypocrellin Fungal antileishmanial inhibit S. aureus Inhibitor Staphylococcus aureus Mycobacterium intracellulare inhibitor