keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hoechst 34580 (HOE 34580), a cell-permeable fluorescent dye, is used for staining DNA and nuclei.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 50.00 | |
5 mg | 5 days | $ 56.00 | |
10 mg | 5 days | $ 82.00 | |
25 mg | 5 days | $ 148.00 | |
50 mg | 5 days | $ 219.00 | |
100 mg | 5 days | $ 302.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 65.00 |
Description | Hoechst 34580 (HOE 34580), a cell-permeable fluorescent dye, is used for staining DNA and nuclei. |
In vitro | Hoechst 34580 is a good candidate for treating Alzheimer's disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner. The IC50 is obtained by measuring the concentration of Hoechst 34580 while maintaining the Aβ42 concentration which gave 0.86±0.05 μM for Hoechst 34580. |
Synonyms | HOE 34580 |
Molecular Weight | 451.57 |
Formula | C27H29N7 |
CAS No. | 23555-00-2 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 47 mg/mL (104.08 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Hoechst 34580 23555-00-2 Neuroscience Beta Amyloid β-amyloid peptide Hoechst34580 HOE34580 Inhibitor HOE-34580 Amyloid-β Hoechst-34580 inhibit Abeta HOE 34580 inhibitor