Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 50.00 | |
100 mg | In stock | $ 63.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2. |
Cell Research | Honokiol is dissolved in DMSO. In cytotoxicity assays, 10,000 cells/well are added to 96 wells plates and incubated overnight, thereafter cells are treated with different concentrations of Honokiol dissolved in dimethylsulphoxide (DMSO). Since Honokiol is not soluble in aqueous solvents, for in vitro studies Honokiol is dissolved in DMSO. To study the possible effect of DMSO on cells, solvent (DMSO) control is used at highest concentration of <0.1%. After 72 h treatment, cells are fixed and cell viability is measured by crystal violet staining (0.05%). |
Source |
Synonyms | NSC 293100 |
Molecular Weight | 266.33 |
Formula | C18H18O2 |
CAS No. | 35354-74-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 26.6 mg/mL (100 mM)
DMSO: 26.6 mg/mL (100 mM)
You can also refer to dose conversion for different animals. More
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Honokiol 35354-74-6 Autophagy Cytoskeletal Signaling MAPK Microbiology/Virology PI3K/Akt/mTOR signaling Proteases/Proteasome MEK Akt ERK HCV Protease Inhibitor inhibit HCV NSC 293100 Hepatitis C virus NSC293100 Protein kinase B PKB NSC-293100 Extracellular signal regulated kinases inhibitor