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Hydroxysafflor yellow A

Catalog No. T3674   CAS 78281-02-4
Synonyms: HSYA, Safflomin A

Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacity and inhibiting the expression of TGF-β. It prevents steroid-induced avascular necrosis of femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells. Also, Hydroxysafflor yellow A has anti-tumor effects.

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Hydroxysafflor yellow A Chemical Structure
Hydroxysafflor yellow A, CAS 78281-02-4
Pack Size Availability Price/USD Quantity
20 mg In stock $ 70.00
1 mL * 10 mM (in DMSO) In stock $ 60.00
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Purity: 99.88%
Purity: 97.1%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacity and inhibiting the expression of TGF-β. It prevents steroid-induced avascular necrosis of femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells. Also, Hydroxysafflor yellow A has anti-tumor effects.
Source
Synonyms HSYA, Safflomin A
Molecular Weight 612.53
Formula C27H32O16
CAS No. 78281-02-4

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (81.63 mM)

TargetMolReferences and Literature

1. Zhu HJ, et al. Cytotechnology. 2015 Oct;67(5):885-92. 2. Yang F, et al. Eur J Pharmacol. 2015 May 5;754:105-14. 3. He Y, et al. J Physiol Biochem. 2015 Mar;71(1):69-78. 4. Liu YL, et al. Int Immunopharmacol. 2014 Dec;23(2):649-57. 6. Jin M, et al. Hydroxysafflor yellow A attenuate lipopolysaccharide-induced endothelium inflammatory injury. Chin J Integr Med. 2015 May 27. 7. Miao T, Qian L, Yu F, et al. Protective effects of hydroxysafflor yellow an on high oxidized low density lipoprotein induced human coronary artery endothelial cells injuries. development. 2019, 22: 581-589.

TargetMolCitations

1. Miao T, Qian L, Yu F, et al. Protective effects of hydroxysafflor yellow an on high oxidized low density lipoprotein induced human coronary artery endothelial cells injuries. Development. 2019, 22: 581-589

Related compound libraries

This product is contained In the following compound libraries:
TGF-beta/Smad Compound Library Anti-Cancer Active Compound Library Cancer Cell Differentiation Compound Library Selected Plant-Sourced Compound Library Anti-Colorectal Cancer Compound Library Bioactive Compounds Library Max Anti-Aging Compound Library Inhibitor Library Traditional Mongolian Medicine Compound Library Ferroptosis Compound Library

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Keywords

Hydroxysafflor yellow A 78281-02-4 Stem Cells TGF-beta/Smad Inhibitor inhibit HSYA Safflomin A inhibitor

 

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