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Hypericin

Catalog No. T6S0923   CAS 548-04-9
Synonyms: Hypericine, Cyclosan

1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Hypericin Chemical Structure
Hypericin, CAS 548-04-9
Pack Size Availability Price/USD Quantity
1 mg In stock $ 52.00
5 mg In stock $ 129.00
10 mg In stock $ 192.00
25 mg In stock $ 382.00
50 mg In stock $ 562.00
100 mg In stock $ 785.00
500 mg In stock $ 1,590.00
1 mL * 10 mM (in DMSO) In stock $ 143.00
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Purity: 99.51%
Purity: 99.17%
Purity: 99.05%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo.
Targets&IC50 tyrosine kinases:7.5 μM
Source
Synonyms Hypericine, Cyclosan
Molecular Weight 504.44
Formula C30H16O8
CAS No. 548-04-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 5 mg/mL (10 mM)), with gentle warming

DMSO: 25.2 mg/mL (50 mM)

TargetMolReferences and Literature

1. Agostinis P , Vantieghem A , Merlevede W , et al. Hypericin in cancer treatment: more light on the way[J]. International Journal of Biochemistry and Cell Biology, 2002, 34(3):0-241.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Clinical Compound Library TGF-beta/Smad Compound Library Tyrosine Kinase Inhibitor Library Anti-Cancer Active Compound Library Miao medicine Compound Library Anti-Cancer Drug Library NO PAINS Compound Library Apoptosis Compound Library Clinical Compound Library Bioactive Compound Library

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Keywords

Hypericin 548-04-9 Apoptosis Chromatin/Epigenetic Cytoskeletal Signaling Immunology/Inflammation Microbiology/Virology Tyrosine Kinase/Adaptors Tyrosine Kinases Antibacterial PKC Antiviral Influenza Virus Dopamine β-monooxygenase antitumor activity Antibiotic antiviral activity telomerase and CYP Telomerase Dopamine beta-monooxygenase MAO Hypericine Protein kinase C fibroblasts CYPs Monoamine Oxidase antidepressive activity Inhibitor Cyclosan monoaminoxidase melanocytes keratinocytes inhibit Dopamine β-hydroxylase Cytochrome P450 Dopamine beta-hydroxylase Reverse Transcriptase Hypericum inhibitor

 

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