Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
2 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 70.00 | |
10 mg | In stock | $ 93.00 | |
25 mg | In stock | $ 198.00 | |
50 mg | In stock | $ 322.00 | |
100 mg | In stock | $ 513.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 72.00 |
Description | Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. |
Synonyms | IY-81149 sodium |
Molecular Weight | 388.42 |
Formula | C19H17N4NaO2S |
CAS No. | 172152-50-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 71 mg/mL(182.8 mM)
H2O: 50 mg/mL (128.73 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
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Ilaprazole sodium 172152-50-0 MAPK Membrane transporter/Ion channel Proton pump TOPK oral Ilaprazole acid ulcers IY 81149 IY-81149 sodium inhibit IY-81149 gastric Inhibitor cancer IY81149 pump Proton Pump inhibitor