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Ingliforib

Catalog No. T8493 CAS 186392-65-4

Synonyms: GPi 296, CP 368296

Ingliforib is a novel glycogen phosphorylase inhibitor,has antihyperglycemic and cardioprotective properties.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Ingliforib, CAS 186392-65-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ingliforib is a novel glycogen phosphorylase inhibitor,has antihyperglycemic and cardioprotective properties.
Targets&IC50	liver Glycogen phosphorylase:52 nM (IC50), Barin Glycogen phosphorylase:150 nM (IC50), Muscle Glycogen phosphorylase:352 nM (IC50)

Synonyms	GPi 296, CP 368296
Molecular Weight	457.91
Formula	C23H24ClN3O5
CAS No.	186392-65-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 125 mg/ml(272.98 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Tracey WR, et al. Cardioprotective effects of ingliforib, a novel glycogen phosphorylase inhibitor. Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H1177-84. 2. Nkansah P , Antipas A , Lu Y , et al. Development and evaluation of novel solid nanodispersion system for oral delivery of poorly water-soluble drugs[J]. Journal of Controlled Release, 2013, 169(1-2):150-161.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compound Library

Related Products

Related compounds with same targets

Ingliforib H-HoArg-OH CP-91149 (-)-p-Bromotetramisole Oxalate Calcium glycerophosphate H-HomoArg-OH.HCl Tracheloside L-Ascorbic acid 2-phosphate magnesium

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ingliforib 186392-65-4 代谢 Phosphorylase Inhibitor GPi 296 GPi296 GPi-296 CP368296 CP-368296 CP 368296 inhibit inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.