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Iniparib

Catalog No. T6224 CAS 160003-66-7

Synonyms: NSC-746045, IND-71677, BSI-201

Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Iniparib, CAS 160003-66-7

Pack Size	Availability	Price/USD
5 mg	In stock	$ 46.00
10 mg	In stock	$ 70.00
25 mg	In stock	$ 128.00
50 mg	In stock	$ 241.00
100 mg	In stock	$ 378.00
200 mg	In stock	$ 600.00
500 mg	In stock	$ 959.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 98.28%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).
Cell Research	Cells are exposed to various concentrations of BSI-201 for 5, and 9 days in the presence or absence of buthionine sulfoxamide (BSO). After treatment, cell proliferation is measured by CellTiter-Glo assay.(Only for Reference)

Synonyms	NSC-746045, IND-71677, BSI-201
Molecular Weight	292.03
Formula	C7H5IN2O3
CAS No.	160003-66-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 14.6 mg/mL (50 mM)

DMSO: 14.6 mg/mL (50 mM)

References and Literature

1. Mendeleyev J, et al. Biochem Pharmacol, 1995, 50(5), 705-714. 2. Bauer PI, et al. Biochem Pharmacol, 2002, 63(3), 455-462. 3. Liu X, et al. Clin Cancer Res, 2012, 18(2), 510-523. 4. Ma W, et al. Proc Natl Acad Sci U S A, 2012, 109(17), 6590-6595. 5. Patel AG, et al. Clin Cancer Res, 2012, 18(6), 1655-1662. 6. Yin S, et al. Myc mediates cancer stem-like cells and EMT changes in triple negative breast cancers cells. PLoS One. 2017 Aug 17;12(8):e0183578.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Drug Repurposing Compound Library Anti-Cancer Active Compound Library Anti-Viral Compound Library Anti-Aging Compound Library NO PAINS Compound Library Anti-Ovarian Cancer Compound Library Bioactive Compound Library

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Related compounds with same targets

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Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Iniparib 160003-66-7 Chromatin/Epigenetic DNA Damage/DNA Repair Microbiology/Virology PARP Influenza Virus NSC-746045 Inhibitor BSI201 inhibit BSI 201 IND-71677 NSC 746045 IND 71677 NSC746045 IND71677 poly ADP ribose polymerase BSI-201 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.