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Ipriflavone

Catalog No. T0309 CAS 35212-22-7

Synonyms: Osteofix, 依普黄酮

Ipriflavone (Osteofix) is a feed additive and a catabolic agent. It is used to inhibit bone resorption.

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Ipriflavone, CAS 35212-22-7

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ipriflavone (Osteofix) is a feed additive and a catabolic agent. It is used to inhibit bone resorption.
Cell Research	Cells are exposed to various concentrations of Ipriflavone for 24, 48, 72 and 96 hours. Cells are treated with trypan blue to estimate the number of viable cells. For thymidine incorporation analysis, [3H]Thymidine (1 μCi) is added, and cells are harvested onto glass fiber filters 4 hours later. Radioactivity is determined by scintillation counting.(Only for Reference)

Synonyms	Osteofix, 依普黄酮
Molecular Weight	280.323
Formula	C18H16O3
CAS No.	35212-22-7

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

Ethanol: 2 mg/mL (7.13 mM)

DMSO: 52 mg/mL (185.5 mM)

H2O: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Cheng SL, et al. Calcif Tissue Int, 1994, 55(5), 356-362. 2. Miyata T, et al. J Am Soc Nephrol, 1997, 8(2), 260-270. 3. Arjmandi BH, et al. Calcif Tissue Int, 2000, 67(3), 225-229. 4. Iwasaki T, et al. Int J Cancer, 2002, 100(4), 381-387. 5. Han, Yuanyuan, et al. Ipriflavone promotes proliferation and osteogenic differentiation of periodontal ligament cells by activating GPR30/PI3K/AKT signaling pathway. Drug design, development and therapy. 2018 Jan 11;12:137-148.

Citations

1. Han Y, Wang X, Ma D, et al. Ipriflavone promotes proliferation and osteogenic differentiation of periodontal ligament cells by activating GPR30/PI3K/AKT signaling pathway. Drug Design Development and Therapy. 2018, 12: 137

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Endocrinology-Hormone Compound Library Inhibitor Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Approved Drug Library Anti-Cancer Drug Library FDA-Approved & Pharmacopeia Drug Library Anti-Aging Compound Library NMPA-Approved Drug Library

Related Products

Related compounds with same targets

4'-Methoxyresveratrol FPS-ZM1 Azeliragon Ipriflavone

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ipriflavone 35212-22-7 其他 advanced glycation end products Inhibitor Osteofix inhibit inhibitor

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