Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 122.00 | |
5 mg | In stock | $ 289.00 | |
10 mg | In stock | $ 455.00 | |
25 mg | In stock | $ 797.00 | |
50 mg | In stock | $ 1,080.00 | |
100 mg | In stock | $ 1,450.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 318.00 |
Description | Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively). |
Targets&IC50 | HIV-1 (MDR):0.15 nM (EC50), HIV-1 (M184V):3.1 nM (EC50), HIV-1 (WT):0.068 nM (EC50) |
Synonyms | MK-8591 |
Molecular Weight | 293.25 |
Formula | C12H12FN5O3 |
CAS No. | 865363-93-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 3 mg/mL (10.23 mM), Sonication and heating to 60℃ are recommended.
DMSO: 100 mg/mL (341.01 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Islatravir 865363-93-5 Microbiology/Virology Proteases/Proteasome Reverse Transcriptase HIV Protease Human immunodeficiency virus Inhibitor inhibit MK-8591 MK8591 MK 8591 HIV inhibitor