Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 102.00 | |
5 mg | In stock | $ 246.00 | |
10 mg | In stock | $ 369.00 | |
25 mg | In stock | $ 622.00 | |
50 mg | In stock | $ 885.00 |
Description | JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body. |
Targets&IC50 | ADAM17:1.9 nM (IC50), MMP8:240 nM (IC50), MMP14:19500 nM (IC50), MMP12:9.4 nM (IC50), ADAM10:150 nM (IC50), MMP9:1630 nM (IC50), MMP9:>500000 nM (IC50), ADAM8:12 nM (IC50) |
Synonyms | JG 26, JG-26 |
Molecular Weight | 594.27 |
Formula | C19H22Br2N4O6S |
CAS No. | 1464910-32-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (84.14 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JG26 1464910-32-4 Immunology/Inflammation Proteases/Proteasome Immunology/Inflammation related MMP JG 26 JG-26 inhibitor inhibit