Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JH-LPH-28, a sulfonyl piperazine analog, is a potent inhibitor of UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH, exhibiting exceptional antibiotic activity with a minimum inhibitory concentration (MIC) value of 0.83 μg/mL.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | Inquiry | Inquiry | |
500 mg | Inquiry | Inquiry |
Description | JH-LPH-28, a sulfonyl piperazine analog, is a potent inhibitor of UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH, exhibiting exceptional antibiotic activity with a minimum inhibitory concentration (MIC) value of 0.83 μg/mL. |
In vitro | JH-LPH-28 effectively suppresses bacterial growth with a concentration as low as 2.8 μg/mL and demonstrates a Minimum Inhibitory Concentration (MIC) of 1.6 μg/mL against wild-type K. pneumoniae. Additionally, it exhibits IC50 values of 0.11 μM against K. pneumoniae LpxH and 0.083 μM against E. coli LpxH, indicating strong inhibitory activity against these bacterial enzymes. |
Molecular Weight | N/A |
CAS No. | 2414592-36-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JH-LPH-28 2414592-36-0 Others JH LPH 28 JHLPH28 inhibitor inhibit