keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 41.00 | |
10 mg | In stock | $ 56.00 | |
25 mg | In stock | $ 96.00 | |
50 mg | In stock | $ 135.00 | |
100 mg | In stock | $ 189.00 |
Description | Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms. |
Source |
Synonyms | 5-Hydroxy-1,4-naphthoquinone, Regianin |
Molecular Weight | 174.15 |
Formula | C10H6O3 |
CAS No. | 481-39-0 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.56 mg/mL (31.9 mM), The compound is unstable in solution and is recommended to be prepared and used immediately.
Ethanol: 15 mg/mL, The compound is unstable in solution and is recommended to be prepared and used immediately.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Juglone 481-39-0 Cell Cycle/Checkpoint DNA Damage/DNA Repair Microbiology/Virology DNA/RNA Synthesis Antibacterial antimicrobial Pigment inhibit Bacterial 5-Hydroxy-1,4-naphthoquinone Inhibitor Yellow black walnut Regianin inhibitor