Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 45.00 | |
2 mg | In stock | $ 64.00 | |
5 mg | In stock | $ 106.00 | |
10 mg | In stock | $ 156.00 | |
25 mg | In stock | $ 289.00 | |
50 mg | In stock | $ 428.00 | |
100 mg | In stock | $ 645.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 122.00 |
Description | KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor. |
In vitro | In cell lines, oxidative stress induced a robust aggregation of α-synuclein,and low concentrations of KYP-2047 significantly reduced the number of cells with α-synuclein inclusions while abolishing the colocalization of α-synuclein and PREP. KYP-2047 significantly reduced the amount of aggregated α-synuclein,and it had beneficial effects on cell viability.?In the transgenic mice, a 5-day treatment with the PREP inhibitor reduced the amount of α-synuclein immunoreactivity and soluble α-synuclein protein in the brain[1]. |
Molecular Weight | 339.43 |
Formula | C20H25N3O2 |
CAS No. | 796874-99-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (73.65 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
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