Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide.
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1 mg | In stock | $ 96.00 | |
5 mg | In stock | $ 188.00 | |
10 mg | In stock | $ 307.00 | |
25 mg | In stock | $ 540.00 | |
50 mg | In stock | $ 779.00 | |
100 mg | In stock | $ 1,090.00 |
Description | Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide. |
In vitro | The peptide kinetensin isolated from pepsin-treated human plasma induces a dose-dependent release of histamine when exposed to rat peritoneal mast cells. The threshold concentration is around 1 μM, the ED50 is 10 μM, and the optimal concentration of between 100 to 1000 μM released 80% of the total histamine. Kinetensin is 10 to 100 times less potent than neurotensin and equipotent with the opioid peptide dynorphin. The histamine release is clearly temperature-dependent, with no release occurring at 0 or 45 °C and with an optimum around 37 °C. The histamine release is significantly reduced in the absence of extracellular calcium[2]. |
In vivo | Kinetensin also induces a dose-dependent increase in vascular permeability when injected intradermally into rats[2]. |
Synonyms | Kinetensin (human) acetate |
Molecular Weight | 1232.45 |
Formula | C58H89N17O13 |
CAS No. | TP1116L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
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Kinetensin acetate(103131-69-7 free base) TP1116L GPCR/G Protein Neurotensin Receptor Kinetensin acetate(103131697 free base) Kinetensin Kinetensin Acetate Kinetensin (human) acetate Kinetensin acetate(103131 69 7 free base) inhibitor inhibit