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Kinetensin acetate(103131-69-7 free base)

Catalog No. TP1116L   CAS TP1116L
Synonyms: Kinetensin (human) acetate

Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide.

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Kinetensin acetate(103131-69-7 free base) Chemical Structure
Kinetensin acetate(103131-69-7 free base), CAS TP1116L
Pack Size Availability Price/USD Quantity
1 mg In stock $ 96.00
5 mg In stock $ 188.00
10 mg In stock $ 307.00
25 mg In stock $ 540.00
50 mg In stock $ 779.00
100 mg In stock $ 1,090.00
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Purity: 100%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide.
In vitro The peptide kinetensin isolated from pepsin-treated human plasma induces a dose-dependent release of histamine when exposed to rat peritoneal mast cells. The threshold concentration is around 1 μM, the ED50 is 10 μM, and the optimal concentration of between 100 to 1000 μM released 80% of the total histamine. Kinetensin is 10 to 100 times less potent than neurotensin and equipotent with the opioid peptide dynorphin. The histamine release is clearly temperature-dependent, with no release occurring at 0 or 45 °C and with an optimum around 37 °C. The histamine release is significantly reduced in the absence of extracellular calcium[2].
In vivo Kinetensin also induces a dose-dependent increase in vascular permeability when injected intradermally into rats[2].
Synonyms Kinetensin (human) acetate
Molecular Weight 1232.45
Formula C58H89N17O13
CAS No. TP1116L

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

TargetMolReferences and Literature

1. Mogard MH, et al. The amino acid sequence of kinetensin, a novel peptide isolated from pepsin-treated human plasma: homology with human serum albumin, neurotensin and angiotensin. Biochem Biophys Res Commun. 1986 May 14;136(3):983-8.

Related compound libraries

This product is contained In the following compound libraries:
Peptide Compound Library Bioactive Compounds Library Max GPCR Compound Library Bioactive Compound Library

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Keywords

Kinetensin acetate(103131-69-7 free base) TP1116L GPCR/G Protein Neurotensin Receptor Kinetensin acetate(103131697 free base) Kinetensin Kinetensin Acetate Kinetensin (human) acetate Kinetensin acetate(103131 69 7 free base) inhibitor inhibit

 

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