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L-838417 D9

Catalog No. T22301 CAS 1213669-91-0

Synonyms: CTP354, CTP354 (C-21191), C-21191

L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].

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L-838417 D9, CAS 1213669-91-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 229.00
5 mg	In stock	$ 485.00
10 mg	In stock	$ 693.00
25 mg	In stock	$ 1,090.00
50 mg	In stock	$ 1,490.00
100 mg	In stock	$ 1,970.00
1 mL * 10 mM (in DMSO)	In stock	$ 585.00

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Purity: 98.81%

Biological Description

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Description

L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].

Synonyms	CTP354, CTP354 (C-21191), C-21191
Molecular Weight	408.45
Formula	C19H10D9F2N7O
CAS No.	1213669-91-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 12 mg/ml (29.38 mM)

References and Literature

1. Hofmann M, et al. Assessment of the effects of NS11394 and L-838417, α2/3 subunit-selective GABA(A) [corrected] receptor-positive allosteric modulators, in tests for pain, anxiety, memory and motor function [published correction appears in Behav Pharmacol. 2013 Apr;24(2):153]. Behav Pharmacol. 2012;23(8):790-801.

Related compound libraries

This product is contained In the following compound libraries：

Membrane Protein-targeted Compound Library Anti-Neurodegenerative Disease Compound Library Antidepressant Compound Library Neurotransmitter Receptor Compound Library Anti-Parkinson's Disease Compound Library Neuronal Signaling Compound Library NO PAINS Compound Library Bioactive Compounds Library Max Ion Channel Inhibitor Library Bioactive Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

L-838417 D9 1213669-91-0 Membrane transporter/Ion channel Neuroscience GABA Receptor L-838417 D-9 CTP 354 CTP354 Inhibitor C 21191 CTP354 (C-21191) CTP-354 inhibit L 838417 D9 L838417 D9 C21191 C-21191 inhibitor

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