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Lanreotide acetate

Catalog No. T8359 CAS 2378114-72-6

Synonyms: Lanreotide acetate (108736-35-2 free base), BIM 23014 (acetate), BIM 23014 acetate

Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome

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Lanreotide acetate, CAS 2378114-72-6

Pack Size	Availability	Price/USD
2 mg	In stock	$ 37.00
5 mg	In stock	$ 59.00
10 mg	In stock	$ 97.00
25 mg	In stock	$ 176.00
50 mg	In stock	$ 262.00
100 mg	In stock	$ 389.00
1 mL * 10 mM (in DMSO)	In stock	$ 133.00

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Purity: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome
In vivo	In a mouse GH3 tumor xenograft model, lanreotide 10 mg/kg moderately inhibited the growth of GH3 tumors, with a 4x tumor growth delay (TGD) time that ranged from 4.5 to 8.3 days. Fractionated local tumor radiation alone significantly inhibited tumor growth and produced a TGD of 35.1+/-5.7 days for 250 cGy fractions[1].
Animal Research	Animal Model:Male nude mice, 8 weeks old and 20–25?g in body weight (GH3 tumor-bearing nude mice).Dosage: 2.5, 5, 10?mg/kg. Administration:Subcutaneous; daily for 5 days[1]

Synonyms	Lanreotide acetate (108736-35-2 free base), BIM 23014 (acetate), BIM 23014 acetate
Molecular Weight	1096.33
Formula	C54H69N11O10S2
CAS No.	2378114-72-6

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 22.5 mg/mL (19.46 mM)

References and Literature

1. Ning S, et al. Lanreotide promotes apoptosis and is not radioprotective in GH3 cells.Endocr Relat Cancer. 2009 Sep;16(3):1045-55. 2. Lo T S , Hammer K D , Zegarra M , et al. Methenamine: a forgotten drug for preventing recurrent urinary tract infection in a multidrug resistance era[J]. Expert Review of Anti Infective Therapy, 2014, 12(5):549-554.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Peptide Compound Library Anti-Cancer Drug Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library FDA-Approved & Pharmacopeia Drug Library Clinical Compound Library Approved Drug Library Bioactive Compound Library

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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