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Lumichrome

Catalog No. T5061 CAS 1086-80-2

Synonyms: 7,8-Dimethylalloxazine

Lumichrome (7,8-Dimethylalloxazine) is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrome can stimulate larval metamorphosis in ascidians and activate the LasR quorum sensing receptor of bacteria. Lumichrome competitively inhibits the uptake of riboflavin by riboflavin transporters from prokaryotes and eukaryotes.

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Lumichrome, CAS 1086-80-2

Pack Size	Availability	Price/USD	Quantity
50 mg	In stock	$ 42.00
100 mg	In stock	$ 66.00

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Purity: 99.69%

Purity: 99.65%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Source

Natural Products > Lamiaceae > Isodon

Synonyms	7,8-Dimethylalloxazine
Molecular Weight	242.23
Formula	C12H10N4O2
CAS No.	1086-80-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

H2O: Soluble

References and Literature

1. Dakora FD, et al. Rhizosphere ecology of lumichrome and riboflavin, two bacterial signal molecules eliciting developmental changes in plants. Front Plant Sci. 2015 Sep 14;6:700. 2. Matiru VN, et al. The rhizosphere signal molecule lumichrome alters seedling development in both legumes and cereals. New Phytol. 2005 May;166(2):439-44. 3. Balcazar DE, et al. The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists. PLoS Negl Trop Dis. 2017 Apr 13;11(4):e202005513.

Related compound libraries

This product is contained In the following compound libraries：

Tobacco Monomer Library RO5 Drug-like Natural Product Library Alkaloid Natural Product Library Human Metabolite Library Natural Product Library for HTS Chinese Pharmacopoeia Natural Product Library Traditional Chinese Medicine Monomer Library Food as Medicine Compound Library Human Endogenous Metabolite Compound Library Plus Selected Plant-Sourced Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Lumichrome 1086-80-2 Others Endogenous Metabolite Inhibitor p53 photodegradation product endogenous 7,8-Dimethylalloxazine Apoptosis human lung cancer cell growth inhibit inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.