Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MGAT2-IN-1 is an orally active monoacylglycerol acyltransferase (MGAT2)inhibitor (human and mouse MGAT2 with IC50 of 7.8 and 2.4 nM , respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 10-14 weeks | $ 469.00 | |
25 mg | 10-14 weeks | $ 1,670.00 | |
50 mg | 10-14 weeks | $ 2,180.00 | |
100 mg | 10-14 weeks | $ 3,480.00 | |
1 mL * 10 mM (in DMSO) | 10-14 weeks | $ 739.00 |
Description | MGAT2-IN-1 is an orally active monoacylglycerol acyltransferase (MGAT2)inhibitor (human and mouse MGAT2 with IC50 of 7.8 and 2.4 nM , respectively). |
Targets&IC50 | MGAT2 (mouse):2.4 nM , MGAT2 (human):7.8 nM |
In vivo | In the lipid utilization analysis, MGAT2-IN-1 significantly increases free fatty acid (FFA) and acylcarnitine levels. MGAT2-IN-1 (30 mg/kg) also significantly reduces food intake dose dependently, suppresses BW gains. MGAT2-IN-1 shows anti-diabetic effects in mice[1]. |
Molecular Weight | 654.01 |
Formula | C27H21ClF5N7O3S |
CAS No. | 1800025-30-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (191.13 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MGAT2-IN-1 1800025-30-2 Others MGAT2 IN 1 MGAT-2-IN-1 MGAT2IN1 inhibitor inhibit