Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MK 0893 is a potent, selective antagonist of glucagon receptor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 8-10 weeks | $ 358.00 | |
25 mg | 8-10 weeks | $ 1,080.00 | |
50 mg | 8-10 weeks | $ 1,410.00 | |
100 mg | 8-10 weeks | $ 2,140.00 |
Description | MK 0893 is a potent, selective antagonist of glucagon receptor. |
Targets&IC50 | Glucagon receptor:6.6 nM |
In vitro | MK 0893 is active against the rhesus monkey GCGR(IC50 of 56 nM in a cAMP assay with CHO cells expressing the rhesus GCGR)[1]. |
In vivo | In hGCGR mice on a high fat diet, MK 0893 at 3, and 10 mpk po in feed lowers blood glucose levels by 89% and 94% at day 10, respectively, relative to the difference between the vehicle control and lean hGCGR mice[1]. |
Molecular Weight | 588.48 |
Formula | C32H27Cl2N3O4 |
CAS No. | 870823-12-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 33.33 mg/mL (56.64 mM)
You can also refer to dose conversion for different animals. More
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MK 0893 870823-12-4 Others MK-0893 MK0893 inhibitor inhibit